Washing hands after lying down on one’s bed:
One who arises from his bed is required to wash his hands [immediately] afterwards. [Some Poskim rule that this applies apply even if one did not sleep at all, but simply got up from relaxing on his bed. This applies even if he lay on his bed during the day. If he laid on his bed without sleeping, he is to wash his hands one time. If he slept for 60 breaths, then he is to wash his hands three times inconsecutively, as explained in Chapter 4 Halacha 20]
 Admur Kama 4:18; Michaber and Beis Yosef 4:18; Abudarham in name of Tashbeitz
 Ketzos Hashulchan 1 supplements page 82; However, see Ohalei Shem 5 p. 133 for an article of Rav Axelrud on this subject, and that he argues on his conclusion. However, in my opinion, the Ketzos Hashulchan seems to be more in the correct.
Background: It is unclear from the wording of Admur “one who arises from his bed” whether it refers to one who has slept or not. It seemingly cannot refer to one who slept for 60 breaths as in such a case he is required to wash his hands three times inconsecutively, as stated in 4:15 [see Chapter 4 Halacha 20], while here Admur clearly rules one only needs to wash his hands one time. Thus, it must either refer to one who did not sleep at all, or slept for less than 60 breaths. This is similar to the law that one who entered a bathroom must wash his hands even if he did not do his needs. The Ketzos Hashulchan concludes it must refer to even one who did not sleep at all. [Ketzos Hashulchan ibid; See however M”B 4:39 who explains that arising from the bed is an exception and hence requires washing three times. This implies that the M”B learns the above Halacha in Shulchan Aruch to refer to one that slept for 60 breaths.]